Such children are distinguished by increased excitability and rapid exhaustion of the nervous system; they have a thin physique, are often overly shy, suffer from neurosis and restless sleep. At the same time, a child with a neuro-arthritic anomaly of the constitution develops speech, memory and other cognitive processes faster than their peers. Children with neuro-arthritic diathesis are prone to impaired metabolism of purines and uric acid, therefore, in adulthood, they are prone to the development of urolithiasis, gout, arthritis, glomerulonephritis, obesity, and type 2 diabetes mellitus.